TSC may refer to:
- The Shadow Confederacy, a small Black alliance founded on April 28, 2008 and which merged into Circle of Icarus on August 9, 2009; or
- The Sandstorm Confederacy, a small multi-colored alliance created from the merging of Sandstorm (formerly The Biohazard Corporation) and the North American Confederacy on March 3, 2014.